Manufacturer: Sinoway
Pharmaceutical name: Myostatin inhibitor ACE-031
Pack: 1 vial (1 mg)
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ACE-031 peptide is a protein that acts as a myostatin inhibitor, designed to mimic a natural receptor responsible for regulating muscle mass, strength, and function. By binding to myostatin and other proteins that influence its function, ACE-031 serves as a blocker of myostatin. Myostatin plays a crucial role in inhibiting the growth and development of muscle cells.
ACE-031 prevents circulating myostatin from attaching to its receptors, thereby stopping the normal process that inhibits muscle growth when myostatin is bound. With ACE-031 blocking this interaction, muscle growth can proceed without restriction. Research involving humans and ACE-031 demonstrated increases in lean muscle mass and muscle volume, alongside positive impacts on fat and bone biomarkers. Multiple pharmaceutical companies are exploring ACE-031 as a potential treatment for various muscle-wasting diseases, such as amyotrophic lateral sclerosis (ALS) and Duchenne muscular dystrophy (DMD). ACE-031 has been identified as a promising therapeutic option for DMD, and myostatin inhibition has emerged as a hopeful strategy in ALS treatment.
ACE-031 is supplied in vials as a powder that must be fully reconstituted with bacteriostatic water. It is essential to inject the water directly into the vial. The vial should not be shaken but can be gently swirled to dissolve any left-over powder. To achieve 1 mg of ACE-031 per 1 ml of solution, add 1 ml of water to dissolve 1 mg of powder. This solution may be administered as a single dose for maximum effect or divided into several smaller doses.
The ACE-031 solution should be refrigerated and can be stored for up to one month. To optimize lean muscle mass growth, doses of ACE-031 can be injected at up to 3 mg/kg. Since ACE-031 has a half-life of up to 15 days, this dosage should not be surpassed within a two-week interval. The best methods for delivering these peptides are through subcutaneous or intramuscular injections.
Treatment with ACE-031 at doses of up to 3 mg/kg has been shown to be safe and well tolerated among healthy individuals. Reported side effects at these concentrations have been mild, with headache being the most frequently noted side effect.